Opportunity Information: Apply for PA 19 126
The Mentored Research Scientist Development Award (K01) from the National Institutes of Health (NIH) is a career development grant designed to help promising researchers build the skills, track record, and mentorship support needed to become independent investigators. The central feature of this award is protected time and structured mentoring for an intensive research and training experience lasting three to five years. It supports career development in the biomedical, behavioral, or clinical sciences, with the goal of moving a candidate from a mentored stage into a position where they can compete successfully for independent research funding.
A key point about this particular announcement, titled "Parent K01 - Independent Clinical Trial Not Allowed" (Funding Opportunity Number PA 19 126), is that it is intended for applicants whose proposed research plan does not involve leading an independent clinical trial. That means the applicant cannot be the person responsible for directing an independent clinical trial, a clinical trial feasibility study, or a separate ancillary clinical trial under this FOA. However, the FOA does allow the candidate to gain experience working on a clinical trial as long as the trial is led by a mentor or co-mentor, which lets applicants build clinical research expertise without taking on the formal leadership role that would trigger the need for a different funding announcement. If an applicant wants to lead a clinical trial (including an ancillary clinical trial) as the lead investigator, they are expected to apply to the companion FOA referenced in the announcement (listed as XXXXX in the provided text).
NIH Institutes and Centers generally use the K01 mechanism to support supervised career development that leads to research independence, but the announcement also notes that some participating NIH components may use the K01 in specific situations. Examples include supporting researchers who want to retrain in a new scientific field or those who have experienced a significant interruption in their research trajectory due to illness or major family responsibilities. The FOA also points out that some NIH components run separate K01 opportunities focused on strengthening diversity in the research workforce, which is distinct from this parent announcement.
In terms of who can apply as an organization, the eligible applicant categories are broad and include many types of U.S.-based entities. Eligible applicants listed include state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofits with and without 501(c)(3) status (other than institutions of higher education); for-profit organizations other than small businesses; small businesses; and a general "others" category. The announcement also explicitly highlights additional eligible institution types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISI). It also mentions faith-based or community-based organizations, eligible federal agencies, regional organizations, certain tribal governments that are not federally recognized, and U.S. territories or possessions.
Foreign eligibility is handled in a specific way. Non-domestic (non-U.S.) entities and non-domestic (non-U.S.) components of U.S. organizations are not eligible to apply as the applicant organization for this FOA. At the same time, the FOA states that foreign components, as defined by the NIH Grants Policy Statement, are allowed. In practical terms, that typically means the prime applicant organization must be eligible and based in the United States, but certain parts of the work may be conducted abroad if they qualify as an allowable foreign component under NIH policy and are well-justified.
The opportunity is categorized as a discretionary grant with an activity category spanning education and health (and related social service areas), and it is associated with multiple CFDA numbers (now commonly referred to under assistance listings), reflecting that multiple NIH Institutes and Centers participate and route funding through different program authorities. The opportunity was created on 2018-12-20, and the original closing date shown in the source data is 2020-05-07. The provided source data does not specify an award ceiling or expected number of awards, which often varies by NIH Institute/Center participation and available appropriations rather than being fixed in the parent announcement itself.
Overall, this FOA is best read as a structured, mentored pathway for research-focused career development: it pays for dedicated effort and training over several years, emphasizes close supervision and progression toward independence, and draws a clear boundary around clinical trial leadership responsibilities by steering would-be trial leaders to a different, companion announcement.Apply for PA 19 126
- The National Institutes of Health in the education, health, income security and social services sector is offering a public funding opportunity titled "Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.172, 93.213, 93.233, 93.273, 93.279, 93.286, 93.837, 93.838, 93.839, 93.840, 93.846, 93.855, 93.865, 93.866.
- This funding opportunity was created on 2018-12-20.
- Applicants must submit their applications by 2020-05-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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| Funding Opportunity |
|---|
| NIH Pathway to Independence Award (Parent K99/R00 - Independent Clinical Trial Required) Apply for PA 19 129 Funding Number: PA 19 129 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Required) Apply for PAR 19 135 Funding Number: PAR 19 135 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $300,000 |
| Accelerating the Pace of Child Health Research Using Existing Data from the Adolescent Brain Cognitive Development (ABCD) Study (R21-Clinical Trial Not Allowed) Apply for PAR 19 163 Funding Number: PAR 19 163 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $200,000 |
| HIV/AIDS Clinical Trials Networks Laboratory Centers (UM1 Clinical Trial Required) Apply for RFA AI 19 001 Funding Number: RFA AI 19 001 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| HIV Prevention Clinical Trials Network Leadership and Operations Center (UM1 Clinical Trial Required) Apply for RFA AI 19 005 Funding Number: RFA AI 19 005 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| HIV/AIDS Clinical Trials Networks Statistical and Data Management Centers (SDMC) (UM1 Clinical Trial Required) Apply for RFA AI 19 002 Funding Number: RFA AI 19 002 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| U.S.-South Africa Program for Collaborative Biomedical Research - Phase 2 (HIV/AIDS) (R01 Clinical Trial Optional) Apply for RFA AI 19 022 Funding Number: RFA AI 19 022 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $350,000 |
| U.S.-South Africa Program for Collaborative Biomedical Research - Phase 2 (HIV/AIDS) (U01 Clinical Trial Optional) Apply for RFA AI 19 023 Funding Number: RFA AI 19 023 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $250,000 |
| BRAIN Initiative: Tools to Facilitate High-Throughput Microconnectivity Analysis (R01 Clinical Trial Not Allowed) Apply for RFA MH 20 135 Funding Number: RFA MH 20 135 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Secondary Analysis and Archiving of BRAIN Initiative Data (R01 Clinical Trial Not Allowed) Apply for RFA MH 20 120 Funding Number: RFA MH 20 120 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $300,000 |
| Brain Initiative: Research to Develop and Validate Advanced Human Cell-Based Assays To Model Brain Structure and Function (R01 Clinical Trial Not Allowed) Apply for RFA MH 20 140 Funding Number: RFA MH 20 140 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $500,000 |
| "Clinical Trials" on a Chip: Tissue Chips to Inform Clinical Trial Design and Implementation in Precision Medicine (UG3/UH3 - Clinical Trial Not Allowed) Apply for RFA TR 19 014 Funding Number: RFA TR 19 014 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $500,000 |
| BRAIN Initiative: Proof of Concept Development of Early Stage Next Generation Human Brain Imaging (R01 Clinical Trial Not Allowed) Apply for RFA EB 19 001 Funding Number: RFA EB 19 001 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $300,000 |
| BRAIN Initiative: Development of Next Generation Human Brain Imaging Tools and Technologies (U01 Clinical Trial not allowed) Apply for RFA EB 19 002 Funding Number: RFA EB 19 002 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Science of Behavior Change (SOBC) Resource and Coordinating Center (U24 Clinical Trial Not Allowed) Apply for RFA AG 20 024 Funding Number: RFA AG 20 024 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Non-Invasive Neuromodulation - New Tools and Techniques for Spatiotemporal Precision (R01 Clinical Trial Optional) Apply for RFA MH 20 310 Funding Number: RFA MH 20 310 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Clinical Sites for the ECHO IDeA States Pediatric Clinical Trials Network - 2 (UG1 Clinical Trial Required) Apply for RFA OD 19 026 Funding Number: RFA OD 19 026 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $275,000 |
| Small Research Grants for Analyses of Gabriella Miller Kids First Pediatric Research Data (R03 Clinical Trial Not Allowed) Apply for PAR 19 375 Funding Number: PAR 19 375 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $200,000 |
| Mobile Health: Technology and Outcomes in Low and Middle Income Countries (R21/R33 - Clinical Trial Optional) Apply for PAR 19 376 Funding Number: PAR 19 376 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Research on biopsychosocial factors of social connectedness and isolation on health, wellbeing, illness, and recovery (R01 Clinical Trials Not Allowed) Apply for PAR 19 373 Funding Number: PAR 19 373 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
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