Opportunity Information: Apply for RFA ES 23 007

The Exploratory Grants for Climate Change and Health Research Center Development (P20 Clinical Trial Optional), Funding Opportunity Number RFA-ES-23-007, is a National Institutes of Health (NIH) grant program designed to help institutions plan and launch Climate Change and Health Research Centers (CCHRCs). It uses the P20 planning grant mechanism, meaning it is aimed less at funding a fully mature center and more at building the foundation for one. The overall goal is to create and strengthen a transdisciplinary research environment that can support sustained, long-term work on how climate change affects human health and how to develop practical, action-oriented solutions that reduce harm and protect people at multiple scales, from individuals to entire communities and nations. The FOA explicitly allows clinical trials but does not require them (clinical trial optional), giving applicants flexibility to propose the types of studies that best fit their planning and capacity-building objectives.

A central emphasis of this opportunity is building new or expanded research capacity by forming teams that cut across disciplines and by working in partnership with communities and other stakeholders. The program is intended to help investigators and institutions organize collaborations, generate early or pilot data, and establish the structures needed for a durable research center. Projects supported through the planning grant are expected to align with the NIH Climate Change and Health Initiative framework and its four core tenets: health effects research (understanding climate-related exposures and their impacts on health), health equity (addressing disproportionate climate burdens and inequities affecting vulnerable or underserved groups), intervention research (developing and testing strategies, programs, or policies that reduce risk and improve resilience), and training and capacity building (developing the workforce, methods, partnerships, and infrastructure needed to sustain the field). In practice, the FOA is geared toward helping applicants move from fragmented efforts to a coordinated center-like program with shared priorities, community-engaged approaches, and a clear pathway toward future, larger-scale research support.

The eligibility for this FOA is broad, reflecting a desire to support many kinds of institutions and communities engaged in climate and health work. Eligible applicants include a wide range of U.S. governmental entities (state, county, city/township, special districts), education organizations (independent school districts, public and state-controlled higher education institutions, private higher education institutions), tribal governments and tribal organizations (including federally recognized tribal governments and other tribal entities), public housing authorities/Indian housing authorities, and nonprofit organizations (both 501(c)(3) and non-501(c)(3)). The FOA also allows for-profit entities (other than small businesses) and small businesses, as well as additional categories such as faith-based or community-based organizations and minority-serving institutions. The announcement explicitly calls out Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), and U.S. territories or possessions. It also notes that non-U.S. entities (foreign organizations) and regional organizations may be eligible, signaling openness to work that addresses climate and health across borders where appropriate.

From a funding standpoint, the opportunity is a discretionary NIH grant with an award ceiling listed at $850,000. It is categorized under multiple CFDA (now Assistance Listing) numbers, indicating participation across NIH components and program areas. The original closing date shown in the source information is November 7, 2023, and the record creation date is March 1, 2023; applicants would typically verify current cycles, reissues, or related active opportunities through NIH and Grants.gov because NIH center-development initiatives are sometimes re-competed or updated over time.

Overall, this FOA is best understood as a center-building and field-building investment. It is meant to help applicants assemble the right scientific and community partnerships, define a coherent climate-and-health research agenda, collect the preliminary data needed to compete for larger awards, and embed equity, intervention development, and training into the center concept from the start. The intended outcome is a stronger national and potentially international ecosystem of climate change and health research centers that can both advance foundational science on climate-related health threats and produce solutions that can be used by communities, health systems, and decision-makers.

  • The National Institutes of Health in the education, environment, health, income security and social services sector is offering a public funding opportunity titled "Exploratory Grants for Climate Change and Health Research Center Development (P20 Clinical Trial Optional)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.233, 93.242, 93.307, 93.361, 93.837, 93.838, 93.839, 93.840, 93.855, 93.865, 93.989.
  • This funding opportunity was created on 2023-03-01.
  • Applicants must submit their applications by 2023-11-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $850,000.00 in funding.
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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FAQs: Exploratory Grants for Climate Change and Health Research Center Development (P20 Clinical Trial Optional) - RFA-ES-23-007

What is RFA-ES-23-007?

RFA-ES-23-007 is a National Institutes of Health (NIH) funding opportunity titled "Exploratory Grants for Climate Change and Health Research Center Development (P20 Clinical Trial Optional)." It supports planning and early-stage development of Climate Change and Health Research Centers (CCHRCs).

What is the purpose of this funding opportunity?

The purpose is to help institutions plan, organize, and launch a transdisciplinary Climate Change and Health Research Center by building foundational capacity. The program is geared toward creating a coordinated, center-like program rather than funding a fully mature, long-standing center.

What does "P20 planning grant" mean in this context?

The P20 mechanism is described here as a planning and capacity-building grant. It is intended to support early center development activities such as organizing collaborations, generating early or pilot data, and establishing structures that enable sustained, long-term climate and health research.

What is a Climate Change and Health Research Center (CCHRC)?

In this opportunity, a CCHRC is a coordinated, center-like program focused on understanding how climate change affects human health and developing practical, action-oriented solutions to reduce harm and protect people at multiple scales (from individuals to communities and nations).

Is a clinical trial required?

No. The FOA is "clinical trial optional," meaning clinical trials are explicitly allowed but not required. Applicants can propose studies that best fit their planning and capacity-building goals.

What types of activities is this grant designed to support?

Based on the description, supported activities focus on building the foundation for a durable center, including forming transdisciplinary teams, establishing community and stakeholder partnerships, generating early or pilot data, and creating the organizational structures needed for a sustained research environment.

What research themes or priorities should projects align with?

Projects are expected to align with the NIH Climate Change and Health Initiative framework and its four core tenets: (1) health effects research, (2) health equity, (3) intervention research, and (4) training and capacity building.

What is meant by "health effects research" in this FOA?

Health effects research refers to understanding climate-related exposures and their impacts on human health.

How does the FOA address health equity?

Health equity is a core tenet. The FOA emphasizes addressing disproportionate climate burdens and inequities that affect vulnerable or underserved groups.

What is meant by "intervention research" here?

Intervention research, as described, involves developing and testing strategies, programs, or policies that reduce climate-related health risks and improve resilience.

What does "training and capacity building" include?

Training and capacity building includes developing the workforce, methods, partnerships, and infrastructure needed to sustain the climate change and health research field and to support a durable center.

Why does the FOA emphasize transdisciplinary teams?

The opportunity is designed to create and strengthen a transdisciplinary research environment. The stated aim is to move from fragmented efforts to coordinated center development by bringing together collaborators across disciplines and linking research with community-engaged approaches.

How important are community and stakeholder partnerships?

They are a central emphasis. The FOA highlights building research capacity through partnerships with communities and other stakeholders, supporting community-engaged approaches and action-oriented solutions.

What outcomes is NIH trying to achieve with this opportunity?

The intended outcomes include stronger and more coordinated climate-and-health research programs, preliminary data and shared priorities that position teams for future larger-scale support, and an expanded ecosystem of research centers capable of advancing science and producing usable solutions for communities, health systems, and decision-makers.

Who is eligible to apply?

Eligibility is broad and includes U.S. governmental entities (state, county, city/township, special districts), education organizations (independent school districts; public/state-controlled, and private higher education institutions), tribal governments and tribal organizations, public housing authorities/Indian housing authorities, and nonprofit organizations (501(c)(3) and non-501(c)(3)).

Are for-profit organizations eligible?

Yes. The FOA allows for-profit entities (other than small businesses) and also allows small businesses.

Are faith-based or community-based organizations eligible?

Yes. The FOA includes eligibility for faith-based or community-based organizations.

Are minority-serving institutions specifically included?

Yes. The FOA explicitly calls out multiple minority-serving institution categories, including Alaska Native and Native Hawaiian Serving Institutions, AANAPISIs, Hispanic-serving Institutions, HBCUs, TCCUs, and it also mentions U.S. territories or possessions.

Are tribal entities eligible?

Yes. The FOA includes federally recognized tribal governments and other tribal entities, as well as tribal organizations and Tribally Controlled Colleges and Universities (TCCUs).

Are non-U.S. (foreign) organizations eligible?

Yes. The FOA notes that non-U.S. entities (foreign organizations) and regional organizations may be eligible, indicating openness to cross-border climate and health work where appropriate.

What is the maximum award amount mentioned?

The opportunity is described as having an award ceiling of $850,000.

Is this considered a discretionary grant?

Yes. It is described as a discretionary NIH grant.

Which agency is offering this funding opportunity?

The program is offered through the National Institutes of Health (NIH).

What is the original closing date listed for this opportunity?

The original closing date shown is November 7, 2023.

Should applicants verify whether the FOA is still open or has been reissued?

Yes. The description notes that applicants would typically verify current cycles, reissues, or related active opportunities through NIH and Grants.gov, since center-development initiatives may be re-competed or updated over time.

What does it mean that multiple CFDA (Assistance Listing) numbers are involved?

It indicates the opportunity is categorized under multiple Assistance Listing numbers, suggesting participation across NIH components and program areas (as described in the summary).

How should this FOA be understood at a high level?

It is best understood as a center-building and field-building investment intended to help applicants assemble scientific and community partnerships, define a coherent climate-and-health research agenda, collect preliminary data for future competitiveness, and embed equity, intervention development, and training into the center concept from the start.

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