Opportunity Information: Apply for PA 17 116
The Chronic Condition Self-Management in Children and Adolescents (R21) funding opportunity (PA 17-116) is a National Institutes of Health (NIH) discretionary grant designed to support exploratory and developmental research aimed at improving how children and adolescents manage chronic health conditions, with the larger goal of enhancing day-to-day functioning and overall quality of life. The central idea behind the announcement is that chronic disease management is not a short-term task or a one-time intervention; it is an ongoing, often lifelong responsibility that children gradually assume alongside their families and caregivers. Because self-management affects medication adherence, symptom monitoring, lifestyle adjustments, school participation, emotional well-being, and family routines, the FOA encourages early-stage studies that can generate new insights, pilot data, or promising approaches that may later be scaled or tested in larger trials.
A defining feature of this opportunity is its emphasis on the many interacting influences that shape self-management in real life. Rather than treating self-management as purely an individual behavior, the FOA explicitly encourages applicants to account for factors such as individual differences and developmental stage, biological and psychological contributors (for example, stress responses, cognition, mental health, and coping), the role of families and caregivers, and the broader sociocultural context that can affect beliefs, access to resources, communication, and trust. It also highlights the importance of looking at how families interact with community settings like schools and youth organizations, and how healthcare system factors (such as care coordination, provider communication, clinic workflows, and continuity of care) can either support or undermine a child or teenager trying to manage a condition over time. In addition, the announcement calls attention to technological advances and environmental influences, leaving room for research that explores how tools like digital health supports, remote monitoring, apps, or other technologies can help, as well as how neighborhood, housing, transportation, or environmental stressors may impact the feasibility of self-management.
The mechanism for this opportunity is the NIH R21, which is typically used for projects that are exploratory in nature and may involve innovative concepts, early feasibility work, or pilot testing. The listed award ceiling is $200,000, signaling that awards are intended to fund smaller, focused projects that can establish proof of concept, refine intervention components, develop measures, test recruitment and retention strategies, or generate preliminary evidence needed for a subsequent larger study. The activity categories connected to the funding include education and health, reflecting the reality that pediatric chronic condition management often spans clinical care, school settings, and family education.
Eligibility is broad and intentionally inclusive, allowing applications from many types of organizations and government entities. Eligible applicants include state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; public housing authorities and Indian housing authorities; Native American tribal organizations other than federally recognized tribal governments; nonprofits with or without 501(c)(3) status (excluding higher education institutions in those nonprofit categories); for-profit organizations other than small businesses; and small businesses. The FOA also explicitly calls out additional eligible applicants such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, U.S. territories or possessions, and even non-U.S. entities (foreign organizations). This wide eligibility reflects NIH interest in attracting ideas and partnerships from diverse settings, including communities that may face distinct barriers to chronic condition self-management and related health outcomes.
Key administrative details included with the opportunity identify NIH as the sponsoring agency, list the CFDA number as 93.361, and note an original closing date of January 24, 2018, with the FOA created on January 9, 2017. Overall, the opportunity is best understood as an invitation to develop and test new, practical approaches for helping children and adolescents live better with chronic conditions by strengthening self-management in ways that reflect the complexity of families, communities, healthcare systems, culture, technology, and the environments where young people grow up.Apply for PA 17 116
- The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Chronic Condition Self-Management in Children and Adolescents (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.361.
- This funding opportunity was created on 2017-01-09.
- Applicants must submit their applications by 2018-01-24. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs)
What is the Chronic Condition Self-Management in Children and Adolescents (R21) opportunity?
This funding opportunity (PA 17-116) is an NIH discretionary grant that supports exploratory and developmental research focused on improving chronic condition self-management among children and adolescents, with the broader goal of improving daily functioning and overall quality of life.
What does the FOA mean by "self-management" for children and adolescents?
In this FOA, self-management is treated as an ongoing, often lifelong responsibility that children gradually take on with support from families and caregivers. It can involve medication adherence, symptom monitoring, lifestyle adjustments, participation in school and activities, emotional well-being, and how family routines adapt over time.
What is the main purpose of this FOA?
The FOA invites early-stage studies that can produce new insights, pilot data, or promising approaches that may later be expanded, scaled, or tested in larger trials.
What type of grant mechanism is used?
The opportunity uses the NIH R21 mechanism, which is typically intended for exploratory, developmental, and early feasibility research, including innovative concepts and pilot testing.
How much funding is available per award?
The listed award ceiling is $200,000, indicating support for smaller, focused projects designed to establish proof of concept or generate preliminary evidence for later, larger studies.
What kinds of projects fit well under an R21 for this topic?
Based on the FOA description, suitable R21 projects may include refining intervention components, developing or improving measures, pilot testing approaches, testing recruitment and retention strategies, conducting early feasibility work, or generating preliminary evidence to support a subsequent larger trial.
Why does the FOA emphasize that self-management is not a one-time intervention?
The FOA frames chronic disease management as a long-term reality rather than a short-term task. Because responsibilities evolve as children develop and contexts change (home, school, healthcare), the research focus is on approaches that can work over time and across real-world settings.
What factors does the FOA encourage applicants to consider when studying self-management?
The FOA explicitly encourages research that accounts for multiple interacting influences, including developmental stage and individual differences; biological and psychological contributors (such as stress responses, cognition, mental health, and coping); family and caregiver roles; sociocultural context affecting beliefs, communication, trust, and resource access; community settings such as schools and youth organizations; and healthcare system factors such as care coordination, provider communication, clinic workflows, and continuity of care.
Does the FOA allow research that involves schools or youth organizations?
Yes. The FOA highlights the importance of examining how families interact with community settings like schools and youth organizations, recognizing that pediatric chronic condition management often extends beyond clinical care.
Does the FOA encourage research on healthcare system barriers and supports?
Yes. The FOA calls attention to healthcare system factors that can support or undermine self-management over time, including care coordination, provider communication, clinic workflows, and continuity of care.
Are technology-based approaches within scope?
Yes. The FOA notes technological advances and leaves room for research exploring digital health supports, remote monitoring, apps, or other technologies that may help children and adolescents manage chronic conditions.
Are environmental or neighborhood factors considered relevant to this FOA?
Yes. The FOA mentions environmental influences and stressors, including factors such as neighborhood conditions, housing, transportation, and other stressors that can affect the feasibility of self-management in everyday life.
What activity categories are associated with this opportunity?
The activity categories connected to the funding include education and health, reflecting that pediatric chronic condition management can involve clinical care, school settings, and family education.
Who is the sponsoring agency for this funding opportunity?
The sponsoring agency is the National Institutes of Health (NIH).
What is the CFDA number listed for this opportunity?
The CFDA number provided is 93.361.
When was the FOA created and what closing date is listed?
The FOA was created on January 9, 2017, and it lists an original closing date of January 24, 2018.
Which types of organizations are eligible to apply?
Eligibility is broad and includes: state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; public housing authorities and Indian housing authorities; Native American tribal organizations other than federally recognized tribal governments; nonprofits with or without 501(c)(3) status (excluding higher education institutions in those nonprofit categories); for-profit organizations other than small businesses; and small businesses.
Are community-based or faith-based organizations eligible?
Yes. The FOA explicitly includes faith-based or community-based organizations among additional eligible applicants.
Are minority-serving institutions specifically identified as eligible applicants?
Yes. The FOA explicitly calls out Alaska Native and Native Hawaiian Serving Institutions, AANAPISISs, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), and other similar entities as eligible applicants.
Can U.S. territories or possessions apply?
Yes. The FOA includes U.S. territories or possessions among additional eligible applicants.
Are non-U.S. (foreign) organizations allowed to apply?
Yes. The FOA states that non-U.S. entities (foreign organizations) are eligible.
Why does the FOA include such broad eligibility?
The FOA indicates that broad eligibility reflects NIH interest in attracting diverse ideas and partnerships from many settings, including communities that may face distinct barriers to chronic condition self-management and related outcomes.
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